Determinants of quality of life in Alzheimer's disease: perspective of patients, informal caregivers, and professional caregivers
| Autor: | Jesús Gómez-Amor, María Gómez-Gallego, Juan Gómez-García |
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| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Attitude of Health Personnel Health Personnel Behavioral Symptoms Disease Irritability Quality of life Alzheimer Disease Sickness Impact Profile Health care medicine Humans Interpersonal Relations Mental Competency Psychiatry Depression (differential diagnoses) Aged Aged 80 and over Psychiatric Status Rating Scales business.industry Perspective (graphical) Cognition Irritable Mood humanities Psychiatry and Mental health Clinical Psychology Cross-Sectional Studies Mood Caregivers Psychotic Disorders Spain Quality of Life Regression Analysis Female Geriatrics and Gerontology medicine.symptom Cognition Disorders business Gerontology Antipsychotic Agents Clinical psychology |
| Zdroj: | International Psychogeriatrics. 24:1805-1815 |
| ISSN: | 1741-203X 1041-6102 |
| DOI: | 10.1017/s1041610212001081 |
| Popis: | Background: Alzheimer's disease (AD) is a chronic medical condition with symptoms that compromise patients’ quality of life (QoL). The identification of the factor predicting QoL in AD is essential to develop more effective interventions. Recent research suggests that these factors could be different for the distinct informants. This study explores the QoL predictors considering three different sources of information: patients, caregivers, and healthcare staff.Methods: In this cross-sectional study, a sample of 102 patients, their primary caregivers, and 15 members of the healthcare staff evaluated patients’ QoL (QoL-AD Scale). Patients’ and caregivers’ demographic and clinical data (cognitive function, neuropsychiatric symptoms, depression, and caregivers’ burden) were considered as QoL predictors.Results: In multivariate-adjusted linear regression analyses, we observed that patients’ ratings were mainly affected by their mood whereas caregivers’ ratings were also negatively influenced by patients’ irritability and burden. According to staff ratings, both psychotic symptoms and neuroleptics were associated with lower QoL.Conclusions: Our findings suggest that depression is the main variable related to patients’ QoL and that more careful management of neuropsychiatric disorders is necessary. Both proxies’ ratings are not equivalent to patients’ reports in terms of predictors but they are complementary. Thus, a thorough QoL assessment should consider separately the perspective of the different informants. |
| Databáze: | OpenAIRE |
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