A Retrospective Multicenter Study of the Natural History of Fetal Ovarian Cysts
Autor: | Stefano Giuliani, Anna L. David, Argyro Syngelaki, Carolina Scala, Kypros H. Nicolaides, Simon Eaton, Athanasios Tyraskis, Mark Davenport, Spyros Bakalis, Paolo De Coppi |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Adult
prenatal aspiration medicine.medical_specialty Prenatal diagnosis Fetal ovarian cyst 03 medical and health sciences 0302 clinical medicine Pregnancy 030225 pediatrics Statistical significance Fetal intervention Ultrasound medicine Humans Cyst Retrospective Studies Gynecology Fetus 030219 obstetrics & reproductive medicine prenatal diagnosis business.industry ultrasound Ovarian torsion General Medicine medicine.disease Prenatal aspiration Exact test Fetal Diseases Ovarian Cysts Pediatrics Perinatology and Child Health ovarian torsion Surgery Female fetal intervention business |
Zdroj: | Tyraskis, A, Bakalis, S, Scala, C, Syngelaki, A, Giuliani, S, Davenport, M, David, A L, Nicolaides, K, Eaton, S & De Coppi, P 2018, ' A Retrospective Multicenter Study of the Natural History of Fetal Ovarian Cysts ', Journal of Pediatric Surgery . https://doi.org/10.1016/j.jpedsurg.2018.02.049 |
DOI: | 10.1016/j.jpedsurg.2018.02.049 |
Popis: | Aim We investigated the natural history of fetal ovarian cysts to estimate the risk of torsion according to size. Methods Cases were identified from 1/1/2000 until 1/1/2015. Data were collected pre- and postnatally on cyst size and sonographic features until an outcome of surgery, torsion, or resolution. Fisher's exact test categorical data and logistic regression for the significance of size on torsion; P value < 0.05 was considered significant. Results 37 patients with unilateral ovarian cysts were included. 12 (32%) resolved spontaneously prenatally, 14 (38%) resolved spontaneously postnatally, 5 (14%) underwent surgery postnatally and 6 (16%) cases underwent torsion. Rate of torsion increased with size from 0% (n = 0) in cysts ≤ 20 mm to 33% (n = 2) in cysts > 50 mm, however, the overall trend failed to reach statistical significance (P = 0.1). Cysts of 0-40 mm had a significantly higher rate of spontaneous resolution (90% vs. 44% in > 40 mm, P = 0.003), but the rate of torsion was not significantly different (10% in 0-40 mm vs. 25% in > 40 mm, P = 0.26). The median time to postnatal resolution was 10 (5–27) weeks in those treated conservatively. Conclusion Cysts > 40 mm are significantly less likely to resolve spontaneously, however torsion showed no significant correlation with cyst size. No complications were observed in cysts < 20 mm. Level of Evidence. IV, case series with no comparison group. |
Databáze: | OpenAIRE |
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