Oxidative Deamination of Benzylamine and Lysine Residue in Bovine Serum Albumin by Green Tea, Black Tea, and Coffee
| Autor: | Kyozo Suyama, Mitsugu Akagawa, Tomoko Shigemitsu |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Benzylamines
Amine oxidase Flavonoid Serum albumin Deamination Coffee chemistry.chemical_compound Phenols Organic chemistry Food science Bovine serum albumin Flavonoids chemistry.chemical_classification Tea biology Autoxidation Lysine Polyphenols food and beverages Serum Albumin Bovine Oxidative deamination Catechin General Chemistry Hydrogen-Ion Concentration chemistry biology.protein General Agricultural and Biological Sciences Oxidation-Reduction Copper |
| Zdroj: | Journal of Agricultural and Food Chemistry. 53:8019-8024 |
| ISSN: | 1520-5118 0021-8561 |
| DOI: | 10.1021/jf050843f |
| Popis: | Oxidative deamination by various polyphenolic compounds is presumed to be due to the oxidative conversion of polyphenols to the corresponding quinones through autoxidation. Here we examined the oxidative deamination by the polyphenol-rich beverages green tea, black tea, and coffee at a physiological pH and temperature. Green tea, black tea, and coffee extracts oxidatively deaminated benzylamine and the lysine residues of bovine serum albumin to benzaldehyde and alpha-aminoadipic delta-semialdehyde residues, respectively, in sodium phosphate buffer (pH 7.4) at 37 degrees C in both the presence and absence of Cu2+, indicating the occurrence of an amine (lysyl) oxidase-like reaction. We also examined the effects of pH and metal ions on the reaction. The possible biological effects of drinking polyphenol-rich beverages on human are also discussed. |
| Databáze: | OpenAIRE |
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