Role of WUSCHEL in Regulating Stem Cell Fate in the Arabidopsis Shoot Meristem
| Autor: | Thomas Laux, Klaus F. X. Mayer, Heiko Schoof, Gerd Jürgens, Achim Haecker, Michael Lenhard |
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| Rok vydání: | 1998 |
| Předmět: |
Plant stem cell
DNA Plant Meristem Molecular Sequence Data Arabidopsis Biology Genes Plant General Biochemistry Genetics and Molecular Biology Gene Expression Regulation Plant Botany Point Mutation Amino Acid Sequence Cloning Molecular Plant Proteins Homeodomain Proteins Base Sequence Arabidopsis Proteins Biochemistry Genetics and Molecular Biology(all) fungi Chromosome Mapping Gene Expression Regulation Developmental food and beverages Cell Differentiation Meristem maintenance biology.organism_classification Cell biology ABC model of flower development Meristem initiation Floral meristem determinacy Stem cell |
| Zdroj: | Cell. 95(6):805-815 |
| ISSN: | 0092-8674 |
| DOI: | 10.1016/s0092-8674(00)81703-1 |
| Popis: | The shoot meristem gives rise to the aerial parts of higher plants by continuously initiating new organs. The basis of this activity is its ability to maintain a pool of pluripotent stem cells, which are the ultimate source of all tissues of the shoot. In Arabidopsis plants mutant for the WUSCHEL (WUS) gene, the stem cells are misspecified and appear to undergo differentiation. Here, we show that WUS encodes a novel homeodomain protein which presumably acts as a transcriptional regulator. The pattern of WUS expression suggests that stem cells in the shoot meristem are specified by an underlying cell group which is established in the 16-cell embryo and becomes localized to its prospective domain of function by asymmetric cell divisions. |
| Databáze: | OpenAIRE |
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