The activity 'in vitro' of trospectomycin against high-level antibiotic-resistant enterococci

Autor: Mario Venditti, A. Tarasi, V. Lamonaca, G.P. Testore, P. Baiocchi
Rok vydání: 1993
Předmět:
Zdroj: International journal of antimicrobial agents. 3(2)
ISSN: 0924-8579
Popis: Trospectomycin, a new aminocyclitol antibiotic, was uniformly active against 69 isolates of enterococci with high-level resistance to steptomycin (54 isolates), gentamicin (27 isolates), ampicillin (19 isolates), ciprofloxacin (17 isolates), vancomycin (3 isolates), or teicoplanin (3 isolates). In time-killing studies, trospectomycin alone demonstrated no bactericidal activity. No synergistic interaction was demonstrated when trospectomycin was combined with ampicillin, vacomycin or ciprofloxacin.
Databáze: OpenAIRE