Ventricular Tachycardia Induced by Propafenone Intoxication in a Pediatric Patient
| Autor: | Vincenzo Tipo, Eduardo Ponticiello, Onorina Di Mita, Pierluigi Marzuillo, Margherita Rosa, Serena Pappacoda, Carolina DʼAnna |
|---|---|
| Přispěvatelé: | Rosa, M., Pappacoda, S., D'Anna, C., Di Mita, O., Ponticiello, E., Marzuillo, P., Tipo, V. |
| Rok vydání: | 2017 |
| Předmět: |
Tachycardia
Male Bicarbonate QT prolongation Propafenone 030204 cardiovascular system & hematology Ventricular tachycardia QT interval 03 medical and health sciences chemistry.chemical_compound Electrocardiography 0302 clinical medicine intoxication medicine Humans 030212 general & internal medicine Sodium bicarbonate medicine.diagnostic_test business.industry General Medicine medicine.disease Pediatric patient Sodium Bicarbonate chemistry Anesthesia Child Preschool Pediatrics Perinatology and Child Health Emergency Medicine Tachycardia Ventricular Administration Intravenous medicine.symptom business Anti-Arrhythmia Agents medicine.drug |
| Zdroj: | Pediatric emergency care. 35(9) |
| ISSN: | 1535-1815 |
| Popis: | Unintentional poisonings are a global health problem frequently resulting in hospital admissions. Propafenone is a class 1C antiarrhythmic drug used in the second-line management of supraventricular and ventricular arrhythmias and, when unintentionally ingested, can lead to severe and life-threatening poisoning. We describe a case of a 3-year-old male patient unintentionally ingesting 300 mg (20 mg/kg) of propafenone and presenting with ventricular tachycardia with QT prolongation. Two boli of intravenous hypertonic sodium bicarbonate (total amount of 3 mEq/kg), followed by 3-hours continuous infusion of 1 mEq kg-1 h-1 sodium bicarbonate, were able to restore the clinical conditions of the patient. With this case report, we aim to highlight the existing challenge in the therapeutic management of propafenone intoxication that finds intravenous hypertonic bicarbonate to be a useful tool also in pediatric population. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|