Primary chest wall tumors: factors affecting survival
| Autor: | Philip E. Bernatz, Jeffrey M. Piehler, W. Spencer Payne, Peter C. Pairolero, Victor F. Trastek, R. Michael King |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Pulmonary and Respiratory Medicine
Thorax Adult Male medicine.medical_specialty Adolescent Chondrosarcoma Fibroma Chest wall resection Rhabdomyosarcoma Medicine Humans Child Aged Lateral chest wall Histiocytoma Benign Fibrous business.industry Respiratory disease Middle Aged Thoracic Neoplasms medicine.disease Surgery El Niño Female Cardiology and Cardiovascular Medicine business Wide resection |
| Zdroj: | The Annals of thoracic surgery. 41(6) |
| ISSN: | 0003-4975 |
| Popis: | Between 1955 and 1975, chest wall resection was done in 90 patients for primary chest wall tumors. Ages ranged from 8 to 96 years (mean, 44.3 years). A painful mass was the most common sign and symptom. Eighty-two tumors (91.1%) were located in the lateral chest wall and eight, in the anterior thorax. The tumor was malignant in 71 patients (78.9%) and benign in 19. All patients with benign tumors had complete excision and are currently free from disease. Malignant fibrous histiocytoma, chondrosarcoma, and rhabdomyosarcoma constituted 62% of the malignant neoplasms. Most malignancies were treated by wide resection. There were no thirty-day operative deaths. Overall 1-, 5-, and 10-year survival was 89%, 57%, and 49%, respectively. Recurrent tumor developed in 37 patients (52%); 5-year survival, however, was only 17% after recurrence. Cell type and extent of invasion significantly influenced survival. Both chondrosarcoma and rhabdomyosarcoma had a better prognosis than malignant fibrous histiocytoma (p less than 0.05). We conclude that early resection is the treatment of choice for primary malignant chest wall tumors and that development of recurrent disease is an ominous event. |
| Databáze: | OpenAIRE |
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