Family history of cancer among children with brain tumors: a critical review
| Autor: | Patricia A. Buffler, Joanna Dearlove, Paul G. Fisher |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Oncology
Adult Male medicine.medical_specialty MEDLINE Risk Factors Internal medicine Medicine Humans Family Family history Child business.industry Brain Neoplasms Case-control study Cancer Hematology medicine.disease Confidence interval Cancer incidence Case-Control Studies Child Preschool Pediatrics Perinatology and Child Health Female business Childhood brain tumor Cohort study |
| Zdroj: | Journal of pediatric hematology/oncology. 30(1) |
| ISSN: | 1077-4114 |
| Popis: | The occurrence of brain tumors in children has been anecdotally associated with an increased cancer incidence among relatives. This study rigorously reviewed the epidemiologic literature regarding family history of cancer in children with brain tumors. Six case-control and 10 cohort studies remained after applying stringent inclusion criteria. Most studies found no significant increase in cancer risk among relatives of childhood brain tumor patients. Those associations that were detected were often of borderline significance or demonstrated wide confidence intervals. There is limited evidence that a family history of cancer is more common among families of childhood brain tumor patients. |
| Databáze: | OpenAIRE |
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