Rodent control programmes can integrate Echinococcus multilocularis surveillance by facilitating parasite genotyping: the case of Arvicola terrestris voles screening in France

Autor: Eric Vannard, Carine Peytavin de Garam, Gérald Umhang, Vanessa Bastid, Jean-Marc Boucher, Jean-Michel Demerson, Léo Legras, Franck Boué, Adrien Pinot, Patrick Giraudoux
Přispěvatelé: Laboratoire de la rage et de la faune sauvage de Nancy (LRFSN), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), GROUPE TETRAS JURA LES BOUCHOUX FRA, Partenaires IRSTEA, Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA), Parc national des Ecrins, Université de Lyon, Rongeurs Sauvages, Risques Sanitaires et Gestion des Populations - UR 1233 (RS2GP), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), ERDF funds (EU), Auvergne Regional Council ('Contribution a la lutte contre les campagnols terrestres' programme)
Rok vydání: 2021
Předmět:
Genotype
Rodent
EmsB genotyping
[SDV]Life Sciences [q-bio]
030231 tropical medicine
Foxes
Zoology
Echinococcus multilocularis
MESH: Echinococcosis
Feces
03 medical and health sciences
0302 clinical medicine
Echinococcosis
biology.animal
Prevalence
medicine
Animals
Parasite hosting
[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology
Arvicola terrestris
Genotyping
030304 developmental biology
MESH: Echinococcus multilocularis
0303 health sciences
Surveillance
MESH: Foxes
General Veterinary
biology
Arvicolinae
business.industry
Host (biology)
Pest control
General Medicine
MESH: Arvicolinae
medicine.disease
biology.organism_classification
Infectious Diseases
Insect Science
Parasitic disease
Rodent Control
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Parasitology
France
business
MESH: Rodent Control
Microsatellite Repeats
Zdroj: Parasitology Research
Parasitology Research, Springer Verlag (Germany), 2021, 120 (5), pp.1903-1908. ⟨10.1007/s00436-021-07126-7⟩
ISSN: 1432-1955
0932-0113
Popis: International audience; The tapeworm Echinococcus multilocularis is the causative agent of alveolar echinococcosis, the most serious parasitic disease for humans in Europe. In Europe, the E. multilocularis lifecycle is based on a prey–predator relationship between the red fox and small rodents. Over the last three decades, the surveillance of E. multilocularis infection in red foxes has led to the description of a wider distribution pattern across Europe. France constitutes the current European western border, but only the north-eastern half of the country is considered endemic. The red fox is the host mainly targeted in E. multilocularis surveillance programmes, but surveys targeting small rodents may be useful for obtaining molecular data, especially when the time-consuming trapping is already carried out in dedicated pest-control programmes. Here, we screened for parasitic lesions in the livers of 1238 Arvicola terrestris voles originating from the historical, but neglected focal area located in central France (Auvergne region) and from Hautes-Alpes, a recently identified endemic department in south-eastern France. This screening identified six voles infected with E. multilocularis in Hautes-Alpes and none in Puy-de-Dôme (Auvergne region) after molecular confirmation. The absence of infected rodents from Puy-de-Dôme can be mainly explained by the generally low prevalence reported in intermediate hosts. The infected Hautes-Alpes samples come all from the same trapping site situated at around 5 km from one of the three fox faecal samples with E. multilocularis DNA collected 15 years prior, thereby confirming the existence and persistence of the E. multilocularis lifecycle in the area. All the rodent E. multilocularis samples from Hautes-Alpes showed the same EmsB microsatellite marker profile. This profile has previously been described in Europe only in the Jura department (central eastern France), located at least 180 km further north. Successive migrations of infected foxes from the historical focal area, including from Jura, to Hautes-Alpes may explain the detection of the parasite in A. terrestris in Hautes-Alpes. Existing trapping efforts in areas where farmers trap A. terrestris for surveillance and pest control can be an effective complement to sampling foxes or fox faeces to obtain E. multilocularis molecular profiles.
Databáze: OpenAIRE
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