STUDIES ON PRESERVED HUMAN BLOOD

Autor: John E. Harris, Robert C. Hardin, Elmer L. DeGowin
Rok vydání: 1940
Předmět:
Zdroj: Journal of the American Medical Association. 114
ISSN: 0002-9955
DOI: 10.1001/jama.1940.02810100024008
Popis: In a previous paper1it was shown that some of the potassium in the erythrocytes of human blood diffused out during storage and that the maximum concentration of that ion in the plasma was approached in fifteen days. The rate or the amount of diffusion was not affected by the type of preservative used or the other conditions of storage studied. The question arose as to whether blood stored for two weeks or more would be toxic when transfused into human beings. Some clinical evidence existed indicating that such blood was not harmful, since various workers had occasionally transfusedaged blood successfully before the phenomenon of potassium diffusion was known. The subject of the toxicity of potassium salts administered intravenously has been reviewed by Scudder, Drew, Corcoran and Bull,2and the reader is referred to their paper for the bibliography. It is undoubtedly true that, if the the concentration of potassium in the blood
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