Prevalence of anti-SARS-CoV-2 antibodies in outpatients of a large public university hospital in Sao Paulo, Brazil
| Autor: | Carina Ceneviva, Laís Teodoro da Silva, Bruna Tiaki Tiyo, Anderson Aparecido Bedin, Luanda Mara da Silva Oliveira, Luiz Augusto Marcondes Fonseca, Telma Miyuki Oshiro, Alexandre de Almeida, Alberto José da Silva Duarte, Vera Aparecida dos Santos, Rosana Coura Rocha |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Pediatrics Serological inquiry 030231 tropical medicine Population RC955-962 Pneumonia Viral Disease Antibodies Viral Asymptomatic Serology 03 medical and health sciences Betacoronavirus 0302 clinical medicine Seroepidemiologic Studies Arctic medicine. Tropical medicine Health care Pandemic Outpatients Prevalence Medicine Humans education Pandemics education.field_of_study business.industry SARS-CoV-2 Public health COVID-19 Anti-SARS-CoV-2 antibodies Original Article medicine.symptom business Coronavirus Infections Brazil Blood sampling |
| Zdroj: | Revista do Instituto de Medicina Tropical de São Paulo Revista do Instituto de Medicina Tropical de São Paulo, Volume: 62, Article number: e91, Published: 13 NOV 2020 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 62 (2020); e91 Revista do Instituto de Medicina Tropical de São Paulo; v. 62 (2020); e91 Instituto de Medicina Tropical (IMT) instacron:IMT Revista do Instituto de Medicina Tropical de São Paulo, Vol 62 (2020) |
| ISSN: | 1678-9946 0036-4665 |
| Popis: | Coronavirus disease 19 (COVID-19) is caused by SARS-Cov-2 and the manifestations of this infection range from an absence of symptoms all the way up to severe disease leading to death. To estimate the prevalence of past infection in a population, the most readily available method is the detection of antibodies against the virus. This study has investigated the prevalence of anti-SARS-CoV-2 antibodies in outpatients of the Hospital das Clinicas, in Sao Paulo city (Brazil), which is a large university hospital belonging to the public health system that cares for patients with complex diseases who need tertiary or quaternary medical care. Our serological inquiry was carried out for 6 weeks, with once-a-week blood sampling and included 439 patients from several outpatient services. Overall, 61 patients tested positive for anti-SARS-CoV-2 IgG (13.9%); 56.1 % of the patients live in Sao Paulo city, with the remaining living in other towns of the metropolitan area; 32.8% of the patients testing positive for IgG antibodies to SARS-CoV-2 were asymptomatic, 55.7% developed mild or moderate disease and 11.5% had to be hospitalized. The prevalence of SARS-CoV-2 positive serology was lower among patients who had received the seasonal influenza vaccine compared to the ones who did not. These findings may indicate that those individuals care more about health issues, and/or that they have a better access to health care and/or a better quality of health care service. The large proportion of patients who were unaware of having had contact with SARS-CoV-2 deserves attention, reflecting the scarcity of tests performed in the population. |
| Databáze: | OpenAIRE |
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