Longitudinal Case Series of Staphylococcus aureus Colonization and Infection in Two Cohorts of Rural Iowans
| Autor: | Shylo E. Wardyn, Dipendra Thapaliya, Ashley E. Kates, Emily J. Hellwig, Tara C. Smith |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Adult Male Methicillin-Resistant Staphylococcus aureus Rural Population medicine.medical_specialty Longitudinal study 030106 microbiology Immunology Skin infection Nose medicine.disease_cause Microbiology 03 medical and health sciences 0302 clinical medicine Antibiotic resistance Risk Factors Internal medicine Epidemiology medicine Humans Colonization 030212 general & internal medicine Longitudinal Studies Aged Skin Pharmacology business.industry Rural health Soft Tissue Infections Middle Aged Staphylococcal Infections medicine.disease Iowa Anti-Bacterial Agents Community-Acquired Infections Staphylococcus aureus Carrier State Pharynx Female Staphylococcal Skin Infections business Cohort study |
| Zdroj: | Microbial drug resistance (Larchmont, N.Y.). 24(4) |
| ISSN: | 1931-8448 |
| Popis: | Examine the relationship between colonization with Staphylococcus aureus in the community and symptomatic infection in two cohorts of Iowans.Case series within cohort study.Rural Iowans selected from the Keokuk Rural Health Study, the Agricultural Health Study, and the Iowa Voter Registry.Longitudinal study within established cohorts evaluating documented S. aureus infections with samples available for molecular typing.We examined this relationship in two cohorts of Iowans with a combined 11 incident cases of S. aureus SSTI, for which samples were available. Seven of the 11 individuals (63.6%) were colonized at baseline, in the nose (3/7, 42.9%), or in both the nose and throat (57.1%). All seven cases had matching sequence types between colonization and infection isolates.Staphylococcus aureus causes millions of skin and soft tissue infections yearly. Although colonization with S. aureus is a frequent antecedent to infection, many studies investigating the link between colonization and infection have taken place in a clinical setting, particularly in urban hospitals. Our study has shown similar results in a rural community setting to those previously seen in clinics. |
| Databáze: | OpenAIRE |
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