Dengue infection in pregnancy and its impact on the placenta
| Autor: | Rita Maria Ribeiro Nogueira, Vânia Glória Silami Lopes, Christiane Fernandes Ribeiro, Roger Denis Rohloff, Andréa Rodrigues Cordovil Pires, Patrícia Brasil |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
0301 basic medicine Microbiology (medical) Adolescent placenta Gestational Age Dengue virus Biology medicine.disease_cause Dengue fever lcsh:Infectious and parasitic diseases Young Adult 03 medical and health sciences 0302 clinical medicine Placenta Decidua medicine Humans lcsh:RC109-216 030212 general & internal medicine Pregnancy Complications Infectious Pregnancy Infant Newborn Pregnancy Outcome Trophoblast General Medicine Dengue Virus medicine.disease Immunohistochemistry dengue Trophoblasts 030104 developmental biology Infectious Diseases medicine.anatomical_structure Products of conception Immunology Female vertical transmission pregnancy |
| Zdroj: | International Journal of Infectious Diseases, Vol 55, Iss C, Pp 109-112 (2017) |
| ISSN: | 1878-3511 1201-9712 |
| Popis: | A histopathological and immunohistochemical study was conducted in placental tissues and retained products of conception from 24 patients with confirmed dengue infection during pregnancy. The immunohistochemical assay was positive for dengue virus in 19 placental and three ovular remnants analyzed. The light microscopic findings were signs of hypoxia, choriodeciduitis, deciduitis and intervillositis and the viral antigens were found in cytoplasmic of the trophoblast, villous stroma and decidua. Our results suggest that immunohistochemistry could be used as a laboratory confirmation method for dengue in pregnant women, especially in endemic areas when embedded material is the only material available. |
| Databáze: | OpenAIRE |
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