Study of CO2 sensitive vagal afferents in the cat lung
| Autor: | Peter Scheid, Kawashiro Takeo, Albert L. Kunz |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Lung CATS Physiology business.industry Respiration Vagus Nerve Carbon Dioxide Electrophysiology Avian lung Endocrinology medicine.anatomical_structure Internal medicine Anesthesia Breathing Cats Medicine Animals business Receptor Lung tissue Mechanoreceptors |
| Zdroj: | Respiration physiology. 27(3) |
| ISSN: | 0034-5687 |
| Popis: | Single unit activity was recorded in the cat vagus in order to detect possible receptors firing in response to changing lung CO 2 concentration. The cats were ventilated at a high rate (60–120 breaths per min) and inspired CO 2 concentration was altered between 0 and 8 % in a step-like fashion, each phase consisting of about 10 breaths. Thus the effects of changing intrapulmonary CO 2 concentration could be differentiated from the effects of stretch of lung tissue. Activity was recorded in 7 cats from 120 units firing in phase with ventilation. Many receptors showed some CO 2 sensitivity, but no fiber was found discharging in response to CO 2 exclusively. The results provide no evidence for the occurence of specific CO 2 receptors in the feline lung with vagal afferents functionally similar to those reported for the avian lung. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|