Epidemiologic analysis: Prophylaxis and multidrug-resistance in surgery

Autor: M. Ramírez-Marino, F.R. Espinoza-López, H. Solís-Téllez, F. Domínguez-Sosa, R.D. Romero-Morelos, E.E. Mondragón-Pinzón, J.F. Rubio-Suarez
Rok vydání: 2017
Předmět:
Zdroj: Revista de Gastroenterología de México (English Edition), Vol 82, Iss 2, Pp 115-122 (2017)
ISSN: 2255-534X
DOI: 10.1016/j.rgmxen.2016.12.002
Popis: Background Surgical site infection is defined as an infection related to the surgical procedure in the area of manipulation occurring within the first 30 postoperative days. The diagnostic criteria include: purulent drainage, isolation of microorganisms, and signs of infection. Aims To describe the epidemiologic characteristics and differences among the types of prophylactic regimens associated with hospital-acquired infections at the general surgery service of a tertiary care hospital. Material and methods The electronic case records of patients that underwent general surgery at a tertiary care hospital within the time frame of January 1, 2013 and December 31, 2014 were reviewed. A convenience sample of 728 patients was established and divided into the following groups: Group 1: n = 728 for the epidemiologic study; Group 2: n = 638 for the evaluation of antimicrobial prophylaxis; and Group 3: n = 50 for the evaluation of multidrug-resistant bacterial strains in the intensive care unit. The statistical analysis was carried out with the SPSS 19 program, using the Mann-Whitney U test and the chi-square test. Results A total of 728 procedures were performed (65.9% were elective surgeries). Three hundred twelve of the patients were males and 416 were females. Only 3.98% of the patients complied with the recommended antimicrobial prophylaxis, and multidrug-resistant bacterial strains were found in the intensive care unit. Discussion A single prophylactic dose is effective, but adherence to this recommendation was not adequate. Conclusions The prophylactic guidelines are not strictly adhered to in our environment. There was a significant association between the development of nosocomial infections from multidrug-resistant germs and admission to the intensive care unit.
Databáze: OpenAIRE