Multiple Approaches to Address Potential Risk Factors of Chagas Disease Transmission in Northeastern Brazil
| Autor: | Helena Keiko Toma, Márcio Neves Bóia, Carolina Coutinho, Rosemere Duarte, Natalia Faria Daflon-Teixeira, Marli Maria Lima, Taís Ferreira Gomes, Filipe Anibal Carvalho-Costa, Carlos Eduardo Almeida |
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| Rok vydání: | 2019 |
| Předmět: |
Chagas disease
Adult Male Nymph Rural Population Adolescent Trypanosoma cruzi 030231 tropical medicine Prevalence Zoology Animals Wild medicine.disease_cause Insect Control Birds 03 medical and health sciences 0302 clinical medicine Risk Factors Virology Infestation parasitic diseases medicine Animals Humans Chagas Disease Triatoma Child Aged Family Characteristics biology Transmission (medicine) Infant Newborn Infant Articles Middle Aged biology.organism_classification medicine.disease Blood meal Triatoma brasiliensis Insect Vectors Infectious Diseases Animals Domestic Child Preschool Parasitology Female Brazil |
| Zdroj: | The American journal of tropical medicine and hygiene. 100(2) |
| ISSN: | 1476-1645 |
| Popis: | Chagas disease is one of the most significant systemic parasitosis in Latin America, caused by Trypanosoma cruzi, which is mainly transmitted by hematophagous insects, the triatomines. This research was carried out in both domestic and wild environments throughout a Northeastern rural locality. Triatomines were captured in both peridomicile and wild environments, obtaining 508 specimens of triatomines, of which 99.6% were Triatoma brasiliensis. Insects were captured in 10 (18.5%) peridomiciles with an average of 8.3 triatomines per residence. Triatoma brasiliensis nymphs and adults were found in six peridomiciles, generating a 11.1% colonization. No T. cruzi infection was detected in the 447 peridomestic insects analyzed. On the other hand, of the 55 sylvatic T. brasiliensis molecularly examined for T. cruzi, 12 (21%) were positive, all harboring T. cruzi I. The blood meal analysis by enzyme-linked immunosorbent assay from gut content revealed that both peridomestic and wild triatomine populations fed mainly on birds, refractory to the parasite, which may explain the null rate of natural infection prevalence in the domestic environment. However, infected triatomines for potential home infestation within the radius of insect dispersion capacity were registered in rock outcrops around the dwellings. Anthropogenic environmental influences are able to rapidly alter these scenarios. Therefore, to avoid disease transmission to humans, we recommend constant vector control combined with periodic serological surveillance. The associated methodology presented herein may serve as a model for early detections of risk factors for Chagas disease transmission in the Brazilian Northeast. |
| Databáze: | OpenAIRE |
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