Initial events in psoriasis: quantitative assessment*
| Autor: | E. Christophers, R Parzefall, O. Braun‐Falco |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Pathology
medicine.medical_specialty Hyperplasia Anthropometry integumentary system medicine.diagnostic_test Biopsy Epidermal hyperplasia Epidermal thickness Dermatology Tritium medicine.disease medicine.anatomical_structure Dermis Psoriasis Quantitative assessment medicine Autoradiography Humans Grain density Mathematics Thymidine |
| Zdroj: | British Journal of Dermatology. 89:327-334 |
| ISSN: | 1365-2133 0007-0963 |
| DOI: | 10.1111/j.1365-2133.1973.tb02986.x |
| Popis: | SUMMARY Seven 3H-TdR-labelled early psoriatic lesions were quantitatively evaluated after serial sectioning and autoradiography. Epidermal thickness was measured planimetrically, whereas labelled cells as well as the number of nuclei present in the dermis were counted. Marked differences in the number of labelled cells as well as in their grain density were observed. These differences correlated with the density of the dermal infiltrate. It is concluded that psoriatic epidermal hyperplasia possibly develops as a response to antecedent and persisting events in the dermis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text