Prenatal serotonin and neonatal outcome: Brief report

Autor: Tiffany Field, Osvelia Deeds, Bárbara Figueiredo, Cynthia M. Kuhn, Angela Ascencio, Saul M. Schanberg, Maria Hernandez-Reif, Miguel Diego
Přispěvatelé: Universidade do Minho
Rok vydání: 2008
Předmět:
Zdroj: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
ISSN: 0163-6383
DOI: 10.1016/j.infbeh.2007.12.009
Popis: Interactions with other systems also occur. Numerous data, for example, have suggested reciprocal interactions between the serotonin system and the hypothalamic-pituitary-adrenal axis (cortisol levels) (Kitamura, Araki & Gomita, 2002; McAllister-Williams, Ferrier & Young, 1998). Dysfunction in serotonergic and glucocorticoid receptors produces lower mood. Dysfunctional interactions between serotonin and dopamine have also been reported (Esposito, 2006; Kalia, 2005; Triviedi, 2006). Lower serotonin and dopamine levels and higher cortisol levels have been noted in a recent study on depressed pregnant women (Field, Diego, Dieter, Hernandez-Reif, Schanberg, Kuhn, Yando & Bendell, 2004). In that study, this biochemical profile in the prenatally depressed women predicted similar profiles in their neonates (Field et al., 2004). The purpose of the present study was to determine the relationships between prenatal serotonin levels and other biochemical values during pregnancy as well as their relationships to neonatal biochemical and behavioral variables. To address that question, the pregnant women were divided into the top and bottom tertiles based on their serotonin levels at 20 weeks gestational age.
Databáze: OpenAIRE