Multi-Tissue Transcriptome Analysis Identifies Key Sexual Development-Related Genes of the Ornate Spiny Lobster (Panulirus ornatus)
| Autor: | Quinn P. Fitzgibbon, Gregory G. Smith, Abigail Elizur, Tuan Viet Nguyen, Cameron J. Hyde, Jennifer C. Chandler, Tomer Ventura |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
lcsh:QH426-470 Doublesex Panulirus ornatus decapod crustaceans Homology (biology) Article Arthropod Proteins 03 medical and health sciences 0302 clinical medicine sexual development Genetic variation Genetics Sexual maturity Animals Palinuridae Sagmariasus Genetics (clinical) sex-linked master sex regulator Sexual differentiation biology doublesex and MAB-3 related transcription factors Gene Expression Profiling Gene Expression Regulation Developmental biology.organism_classification lcsh:Genetics 030104 developmental biology Evolutionary biology Transcriptome Spiny lobster 030217 neurology & neurosurgery |
| Zdroj: | Genes Genes, Vol 11, Iss 1150, p 1150 (2020) Volume 11 Issue 10 |
| ISSN: | 2073-4425 |
| Popis: | Sexual development involves the successive and overlapping processes of sex determination, sexual differentiation, and ultimately sexual maturation, enabling animals to reproduce. This provides a mechanism for enriched genetic variation which enables populations to withstand ever-changing environments, selecting for adapted individuals and driving speciation. The molecular mechanisms of sexual development display a bewildering diversity, even in closely related taxa. Many sex determination mechanisms across animals include the key family of &ldquo doublesex- and male abnormal3-related transcription factors&rdquo (Dmrts). In a few exceptional species, a single Dmrt residing on a sex chromosome acts as the master sex regulator. In this study, we provide compelling evidence for this model of sex determination in the ornate spiny lobster Panulius ornatus, concurrent with recent reports in the eastern spiny lobster Sagmariasus verreauxi. Using a multi-tissue transcriptomic database established for P. ornatus, we screened for the key factors associated with sexual development (by homology search and using previous knowledge of these factors from related species), providing an in-depth understanding of sexual development in decapods. Further research has the potential to close significant gaps in our understanding of reproductive development in this ecologically and commercially significant order. |
| Databáze: | OpenAIRE |
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