Independent association between low serum amylase and non-alcoholic fatty liver disease in asymptomatic adults: a cross-sectional observational study
| Autor: | Hiroshi Fuchigami, Toshitaka Muneyuki, Kei Nakajima, Haruki Oshida, Hiromi Munakata, Yumiko Hori, Masafumi Kakei, Masafumi Saito |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Pathology Epidemiology Non-obesity Gastroenterology Asymptomatic Insulin resistance Diabetes mellitus Internal medicine NAFLD medicine Clinical Epidemiology Obesity Cross sectional studies business.industry Research Fatty liver General Medicine medicine.disease Quartile Serum amylase Metabolic syndrome medicine.symptom business Body mass index |
| Zdroj: | BMJ Open |
| ISSN: | 2044-6055 |
| Popis: | OBJECTIVES: Low serum amylase (LSA) was reported to be associated with obesity, metabolic syndrome (MetS) and diabetes. However, it is unknown as to whether LSA is associated with non-alcoholic fatty liver disease (NAFLD), a hepatic manifestation of MetS and insulin resistance. Therefore, we performed a clinical epidemiological study to investigate this potential association. DESIGN: A cross-sectional observational study with multivariate analysis. SETTING: Subjects were recruited in a healthcare centre in Saitama, an eastern district of Japan, near Tokyo. PARTICIPANTS: A total of 1475 asymptomatic adults aged 30-79 years who underwent detailed medical check-ups and who regularly consumed small amounts of alcohol ( Free PMC Article. Open Access. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|