Characteristics of the 24-h ambulatory blood pressure monitoring in patients with Parkinson's disease – the SFC BP multicentre study in China
| Autor: | Shi-Wu Chen, Nan Ding, Rong-Hua Dou, Hai-Fang Jing, Xin-Yi Xie, Yan Xue, Yan Li, Wei-Dong Zhao, Guo-Hua Zhang, Gang Wang, Yong-Bo Hu, Yu-Kai Wang |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
China medicine.medical_specialty Parkinson's disease Ambulatory blood pressure Physiology Diastole Blood Pressure Disease 030204 cardiovascular system & hematology Cohort Studies Hypotension Orthostatic 03 medical and health sciences Orthostatic vital signs 0302 clinical medicine Internal medicine Internal Medicine medicine Humans In patient 030212 general & internal medicine Aged business.industry Dysautonomia Parkinson Disease Blood Pressure Monitoring Ambulatory Middle Aged medicine.disease Cohort Cardiology Female medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Hypertension. 38:2270-2278 |
| ISSN: | 1473-5598 0263-6352 |
| Popis: | OBJECTIVES Cardiovascular dysautonomia can be present at early, late and even prodromal stages of Parkinson's disease. This study aimed to describe the characteristics of 24-h ambulatory blood pressure (BP) monitoring and investigate the frequency of cardiovascular dysautonomia in Parkinson's disease without an abnormal BP history. METHODS Parkinson's disease patients without history of abnormal BP were consecutively enrolled from three Chinese centres, on whom office BP measurement, neurological evaluations and 24-h ambulatory BP monitoring were performed. RESULTS Totally, 101 Parkinson's disease patients (42.6% women) with an average age of 66.6 ± 8.2 years were included in our cohort, and data analysis revealed that 26 (25.74%) patients suffered from orthostatic hypotension, among whom 18 (69.23%) were symptomatic. Patients with orthostatic hypotension compared with those without had significantly higher nocturnal SBP level, and more severe nonmotor symptoms, autonomic dysfunction and cognitive impairment. Further, 54 out of 101 (53.47%) individuals had a reverse dipping pattern in SBP and/or DBP. Reverse dippers had more cases of orthostatic hypotension (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|