Fetal pulmonary maturity as determined by fluorescent polarization of amniotic fluid
| Autor: | H, Elrad, S N, Beydoun, J H, Hagen, M T, Cabalum, R H, Aubry, C, Smith |
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| Rok vydání: | 1978 |
| Předmět: |
Risk
Pathology medicine.medical_specialty Amniotic fluid Prenatal diagnosis Fluorescence Polarization Gestational Age Andrology Microviscosity Pregnancy Prenatal Diagnosis medicine Humans Lung Hyaline Fetus Respiratory Distress Syndrome Newborn business.industry Viscosity Infant Newborn Obstetrics and Gynecology Gestational age medicine.disease Amniotic Fluid Sphingomyelins Pregnancy Complications medicine.anatomical_structure Phosphatidylcholines Female business |
| Zdroj: | American journal of obstetrics and gynecology. 132(6) |
| ISSN: | 0002-9378 |
| Popis: | A special technique, fluorescent polarization (F.P.) has been used to measure the microviscosity of amniotic fluid. A total of 151 samples of amniotic fluid from 118 patients, both normal and high-risk, were included in this study. The results were compared to L/S ratios and to the neonatal outcomes. The F.P. value was found to decrease as pregnancy progressed, and a value of 0.345 or less was found to be associated with apparent fetal lung maturity. The correlation between the F.P. value and the L/S ratio was good when mature results were compared (L/S >2 and F.P.≤0.345). When the L/S ratio was immature ( 345) developed RDS and three of these died with hyaline membrane disease. In 83 patients delivered within 48 hours of the amniotic fluid sampling, the predictive value of the F.P. increased to 100 per cent but that of the L/S ratio remained 14 per cent. |
| Databáze: | OpenAIRE |
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