| Autor: |
Sumiyo Saburi, Takahiro Tsujikawa, Aya Miyagawa-Hayashino, Junichi Mitsuda, Kanako Yoshimura, Alisa Kimura, Hiroki Morimoto, Gaku Ohmura, Akihito Arai, Hiroshi Ogi, Eiichi Konishi, Kyoko Itoh, Kiminori Sugino, Shigeru Hirano |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 35(6) |
| ISSN: |
1530-0285 |
| Popis: |
Spatial profiles of the tumor-immune microenvironment are associated with disease progression and clinicopathological factors in various cancers. Follicular thyroid carcinoma (FTC) is the second most common thyroid cancer, where the presence of capsular invasion or angioinvasion determines the pathological diagnosis; however, little is known about the immune microenvironment profiles associated with the acquisition of invasive potential of FTC. In this study, we focused on FTC with minimal capsular invasion, and the spatially resolved immune microenvironment of FTC was studied in the discovery (n = 13) and validation cohorts (n = 40). CD8 |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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