Short-term outcomes of transcatheter closure of secundum atrial septal defect in children and adolescents: An experience of two centers in Upper Egypt
| Autor: | Salah-Eldin Amry, Sharaf E.D. Mahamoud, Duaa M. Raafat, Safaa Husein Ali, Amal M. El Sisi |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Short-term outcomes lcsh:Diseases of the circulatory (Cardiovascular) system medicine.medical_treatment Septum secundum Atrial septal defect closure 030204 cardiovascular system & hematology 03 medical and health sciences Heart block 0302 clinical medicine Interquartile range Internal medicine Ductus arteriosus medicine 030212 general & internal medicine Embolization business.industry Retrospective cohort study medicine.disease Surgery Stenosis medicine.anatomical_structure lcsh:RC666-701 Adverse events Balloon dilation Cardiology Original Article business Interatrial septum |
| Zdroj: | Journal of the Saudi Heart Association, Vol 30, Iss 1, Pp 14-20 (2018) |
| ISSN: | 1016-7315 |
| Popis: | Background The aim of this study was to evaluate the acute and short-term outcomes of transcatheter closure of secundum atrial septal defect (ASD) in children and adolescents in the first 4-year experience in two institutional centers in Upper Egypt. Methods This was a retrospective cohort study including 135 children and adolescents who underwent ASD closure between April 2012 and May 2016. A review of the acute and short-term outcomes and adverse events was performed. Results The patients had a median age of 5 years (interquartile range: 3–9 years), 71% of patients were ≤5 years, and median weight was 17 kg (interquartile range: 13–30 kg). Single defects were observed in 113 patients (84%). The remainder had multiple or multifenestrated defects that were closed by a single device. The mean defect size of single defects and the mean interatrial septum length were 15.24 ± 5.16 mm and 38.13 ± 6.3 mm, respectively. The ratio of device to TEE (Transoesophageal echocardiography) size of ASD was 1.19 ± 0.12. The devices were implanted successfully in 98.5% of patients. Six cases had concordant PS (Pulmonary stenosis), patent ductus arteriosus or perimembranous ventricular septal defect and were treated with balloon dilation, or closure. No residual flow was seen after device placement except in one patient with multiple fenestrations. There were five high-severity adverse events (3.7%) with no mortality. Device erosion was confirmed in one of two patients with massive haemopericardium; embolization of the device with retrieval in one patient; and heart block was detected in two cases. No cardiac perforation, device erosion, embolization, thrombus formation, or clinical evidence of bacterial endocarditis was observed during follow-up. Conclusions Transcatheter closure of ASDs in children and adolescents was feasible and safe in the first 4 years experience in our centers, with good short-term outcome. Balloon sizing is not necessary for transcatheter closure of secundum ASD. Multiple defects can be safety closed by a single device. |
| Databáze: | OpenAIRE |
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