Evaluation of 5 Commercially Available Zika Virus Immunoassays

Autor: Kimberly Holloway, Kai Makowski, Joanne Hiebert, Sharla Beddome, Michael A. Drebot, Rhonda Mogk, Nicole Barairo, Emelissa J Mendoza, Alyssia Robinson, David Safronetz, Charlene Ranadheera, Angela Sloan, Leanne Scharikow, Elizabeth Giles, Kristina Dimitrova, Derek R. Stein, Maya Traykova-Andonova
Rok vydání: 2017
Předmět:
Zdroj: Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 23, Iss 9, Pp 1577-1580 (2017)
ISSN: 1080-6059
1080-6040
DOI: 10.3201/eid2309.162043
Popis: Because of the global spread of Zika virus, accurate and high-throughput diagnostic immunoassays are needed. We compared the sensitivity and specificity of 5 commercially available Zika virus serologic assays to the recommended protocol of Zika virus IgM-capture ELISA and plaque-reduction neutralization tests. Most commercial immunoassays showed low sensitivity, which can be increased.
Databáze: OpenAIRE