Prognostic factors for candidaemia in intensive care unit patients: a retrospective analysis
| Autor: | Mariko Mizunuma, Hiroyasu Ishikura, Reiko Yamasaki, Takeshi Nishida, Yoshihiko Nakamura, Atsushi Togawa, Kota Hoshino, Yasumasa Kawano |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Organ Dysfunction Scores 030106 microbiology Risk Assessment law.invention Tertiary Care Centers Young Adult 03 medical and health sciences 0302 clinical medicine Japan Risk Factors law medicine Humans 030212 general & internal medicine Intensive care medicine Aged Candida Retrospective Studies Aged 80 and over Receiver operating characteristic business.industry Medical record Mortality rate Candidemia Retrospective cohort study General Medicine Middle Aged Prognosis Intensive care unit Confidence interval Intensive Care Units ROC Curve Emergency medicine Female Original Article SOFA score Risk assessment business |
| Zdroj: | Singapore Medical Journal. 58:196-200 |
| ISSN: | 0037-5675 |
| DOI: | 10.11622/smedj.2016113 |
| Popis: | INTRODUCTION Candidaemia, recognised as a fairly common disease among intensive care unit (ICU) patients, carries a poor prognosis. However, as studies on the prognostic factors associated with candidaemia in ICU patients are limited, this study aimed to establish the best prognostic factor for ICU patients with candidaemia in a tertiary care hospital in Japan. METHODS We conducted a retrospective cohort study of patients with candidaemia in the emergency ICU at Fukuoka University Hospital, Fukuoka, Japan, from April 2010 to March 2015. Demographic and clinical data was collected from the patients' medical records and laboratory databases. RESULTS A total of 25 patients were included in the study. However, 18 patients died during hospitalisation, resulting in an in-hospital mortality rate of 72.0%. The variables of Sequential Organ Failure Assessment (SOFA) score and cumulative number of risk factors for invasive candidiasis showed significant differences between patients in the survivor and non-survivor groups (p < 0.05). The areas under the receiver operating characteristic curves for the SOFA score and cumulative number of risk factors for invasive candidiasis were 0.873 (95% confidence interval [CI] 0.72-1.00) and 0.937 (95% CI 0.84-1.00), respectively. CONCLUSION Our results suggest that the cumulative number of risk factors for invasive candidiasis was the most useful prognostic indicator for candidaemia in ICU patients. |
| Databáze: | OpenAIRE |
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