Successful management of CMV pneumonia in a mechanically ventilated patient
| Autor: | David Emanuel, Graziano C. Carlon, Steven Sommer, Jeffrey S. Groeger |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Pulmonary and Respiratory Medicine
Ganciclovir Adult medicine.medical_specialty Combination therapy medicine.medical_treatment Pneumonia Viral Congenital cytomegalovirus infection Critical Care and Intensive Care Medicine Postoperative Complications medicine Humans Pneumonitis Bone Marrow Transplantation medicine.diagnostic_test business.industry CMV Pneumonia Immunization Passive Immunotherapy medicine.disease Respiration Artificial Surgery Bronchoalveolar lavage Respiratory failure Cytomegalovirus Infections Female Cardiology and Cardiovascular Medicine business Respiratory Insufficiency medicine.drug |
| Zdroj: | Chest. 100(3) |
| ISSN: | 0012-3692 |
| Popis: | We report a case of severe respiratory failure due to cytomegalovirus pneumonitis in a patient who underwent an allogeneic bone marrow transplant, who was successfully treated with the combination of ganciclovir and high-dose intravenous immune globulin. We also reviewed the rationale for the use of combination therapy with an antiviral agent and immunotherapy. Because of the bone marrow toxicity of ganciclovir, an aggressive diagnostic approach, including bronchoalveolar lavage and open lung biopsy, may be necessary to establish a definitive diagnosis prior to institution of therapy. (Chest 1991; 100:856-58) |
| Databáze: | OpenAIRE |
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