Recurrence rate and clinical outcome of amniotic membrane transplantation combined with mitomycin c in pterygium surgery: Two-year follow-up
| Autor: | Mohsen Pourazizi, Majid Mirmohammadkhani, Seyed-Abolfazl Kashfi, Hasan Razmjoo |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Pterygium surgery lcsh:RS1-441 030226 pharmacology & pharmacy lcsh:Pharmacy and materia medica Lesion 03 medical and health sciences 0302 clinical medicine Medicine pterygium 030212 general & internal medicine mitomycin business.industry Mitomycin C Outcome measures General Medicine Size change medicine.disease Surgery Pterygium Transplantation Standard protocol Original Article sense organs amniotic membrane transplantation medicine.symptom business recurrence risk |
| Zdroj: | Journal of Research in Pharmacy Practice, Vol 9, Iss 1, Pp 10-15 (2020) Journal of Research in Pharmacy Practice |
| ISSN: | 2319-9644 |
| DOI: | 10.4103/jrpp.jrpp_19_127 |
| Popis: | Objective: To evaluate the recurrence rate and outcome of pterygium surgery with amniotic membrane transplantation (AMT) and intraoperative mitomycin C (MMC). Methods: This prospective clinical study included patients with pterygium who were candidates for pterygium excision. After the surgical excision, intraoperative local MMC were applied in the standard protocol followed by AMT. The outcome measures were recurrence and the size change of lesion. Kaplan-Meier estimation and regression analyses were performed. Findings: Fifty five eyes of 55 consecutive patients including 30 male (54.5%) and 25 female (45.5%) with mean age of 47.12 ± 15.95 years were operated. The mean follow-up period was 15.21 ± 2.67 months. The overall recurrence rate was 34.5% (19/55 cases). The estimated recurrence time for larger size of pterygium before surgery was short and marginally significant (17.14 ± 0.58 month in size of ≤3.0 mm versus. 18.56 ± 0.60 month in size of |
| Databáze: | OpenAIRE |
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