Effects of Calcium-Channel Blocker Benidipine-Based Combination Therapy on Cardiac Events ― Subanalysis of the COPE Trial ―

Autor:	Masunori Matsuzaki, Takao Saruta, Toshio Ogihara, Kazuyuki Shimada, Seiji Umemoto, Kazuomi Kario, Masatoshi Kawana, Hiromi Rakugi, Yasuo Ohashi
Rok vydání:	2018
Předmět:	Male Dihydropyridines medicine.medical_specialty Heart Diseases Combination therapy medicine.drug_class Adrenergic beta-Antagonists Calcium channel blocker 030204 cardiovascular system & hematology Pharmacology Thiazides 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine Humans 030212 general & internal medicine Antihypertensive Agents Thiazide Aged business.industry Hazard ratio Dihydropyridine General Medicine Middle Aged Calcium Channel Blockers Treatment Outcome Blood pressure chemistry Hypertension Benidipine Cardiology Drug Therapy Combination Female Cardiology and Cardiovascular Medicine business Angiotensin II Type 1 Receptor Blockers medicine.drug
Zdroj:	Circulation Journal. 82:457-463
ISSN:	1347-4820 1346-9843
Popis:	BACKGROUND The Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) trial was conducted to compare the effects of regimens combining the dihydropyridine calcium-channel blocker benidipine with each of 3 secondary agent types (an angiotensin-receptor blocker (ARB), a β-blocker and a thiazide) in Japanese hypertensive outpatients who did not achieve target blood pressure (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9299040f5fa7ff2ce5d4e9d36bfebe3 https://doi.org/10.1253/circj.cj-17-0592 Zobrazit plný text záznamu