Exercise prevents fatigue and improves quality of life in prostate cancer patients undergoing radiotherapy
| Autor: | Carlos Vallbona, John Thornby, Kuno P. Zimmermann, Uma Monga, Trilok N. Monga, Anthony J. Kerrigan, Susan L. Garber |
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| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Physical Therapy Sports Therapy and Rehabilitation Physical exercise law.invention Prostate cancer Randomized controlled trial Quality of life law Aerobic exercise Medicine Humans Prospective Studies Prospective cohort study Pliability Cardiovascular fitness Exercise Fatigue Aged Aged 80 and over business.industry Rehabilitation Cancer Prostatic Neoplasms Middle Aged medicine.disease Physical Fitness Physical therapy Exercise Test Quality of Life business |
| Zdroj: | Archives of physical medicine and rehabilitation. 88(11) |
| ISSN: | 1532-821X |
| Popis: | Monga U, Garber SL, Thornby J, Vallbona C, Kerrigan AJ, Monga TN, Zimmermann KP. Exercise prevents fatigue and improves quality of life in prostate cancer patients undergoing radiotherapy. Objective To show fatigue prevention and quality of life (QOL) improvement from cardiovascular exercise during radiotherapy. Design Prospective enrollment (n=21), randomized to exercise (n=11) and control groups (n=10), with pre- and post-radiotherapy between- and within-group comparisons. Setting Academic medical center. Participants Localized prostate cancer patients undergoing radiotherapy. Interventions The interventional group received radiotherapy plus aerobic exercise 3 times a week for 8 weeks whereas the control group received radiotherapy without exercise. Main Outcome Measures Pre- and post-radiotherapy differences in cardiac fitness, fatigue, depression, functional status, physical, social, and functional well-being, leg strength, and flexibility were examined within and between 2 groups. Results No significant differences existed between 2 groups at pre-radiotherapy assessment. At post-radiotherapy assessment, the exercise group showed significant within group improvements in: cardiac fitness ( P P =.02), Functional Assessment of Cancer Therapy–Prostate (FACT-P) ( P =.04), physical well-being ( P =.002), social well-being ( P =.02), flexibility ( P =.006), and leg strength ( P =.000). Within the control group, there was a significant increase in fatigue score ( P =.004) and a decline in social well-being ( P P =.006), strength ( P =.000), flexibility ( P P P =.006), physical well-being ( P P =.002), and functional well-being ( P =.04). Conclusions An 8-week cardiovascular exercise program in patients with localized prostate cancer undergoing radiotherapy improved cardiovascular fitness, flexibility, muscle strength, and overall QOL and prevented fatigue. |
| Databáze: | OpenAIRE |
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