Lung function in patients with inflammatory bowel disease
| Autor: | Demosthenes Bouros, John Mouzas, P. Panagou, Maria Samiou, O. Manousos, Nikolaos Tzanakis, Nikos M. Siafakas |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Vital Capacity Disease Gastroenterology Inflammatory bowel disease Pulmonary function testing Crohn Disease DLCO Internal medicine Forced Expiratory Volume medicine Humans Colitis Lung business.industry Respiratory disease respiratory system medicine.disease Ulcerative colitis respiratory tract diseases Residual Volume medicine.anatomical_structure Immunology Colitis Ulcerative Female business Lung Volume Measurements |
| Zdroj: | Respiratory Medicine. 92(3):516-522 |
| ISSN: | 0954-6111 |
| DOI: | 10.1016/s0954-6111(98)90301-8 |
| Popis: | Previous studies on baseline pulmonary function testing (PFT) abnormalities in patients with inflammatory bowel disease (IBD) are conflicting because most of them have incorporated patients suffering from both ulcerative colitis (UC) and Crohn's disease (CD). The aim of the study is to investigate whether any PFT abnormalities could be detected in a large group of IBD patients and whether there are differences between the two IBD entities. A total of 132 patients, 47 with CD (mean age 35 years) and 85 with UC (mean age 40 years) were studied. Pulmonary function tests (PFTs), lung transfer factor for carbon monoxide (TlCO) were examined and compared with those of 36 healthy controls. No significant difference of mean values of spirometric indices, TlCO and ABG was found between the two groups of patients and controls, or between patients with CD and UC. However, nine (19%) patients with CD and 15 (17·6%) with UC had a reduction in TlCO, a percentage significantly higher than in controls (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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