Analysis of factors affecting short-term results in elderly patients undergoing elective surgical resection for stage I-II colon cancer
| Autor: | Paolo Ubiali, Patrizio Pianon, Giovanni Fanti, Stefano M.M. Basso, Franco Lumachi, Federica Maffeis |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Surgical resection
Adult Male medicine.medical_specialty Cancer Research Complications Colorectal cancer Comorbidity Adenocarcinoma Group B Comorbidities 03 medical and health sciences 0302 clinical medicine Elderly Postoperative Complications Risk Factors Neoplasms medicine 80 and over Humans 030212 general & internal medicine Stage (cooking) Cancer Aged Neoplasm Staging Aged 80 and over Polypharmacy business.industry Age Factors Malignancy General Medicine Cancer Malignancy Neoplasms Colorectal cancer Comorbidities Complications Elderly Short-term results Adenocarcinoma Adult Age Factors Aged Aged 80 and over Colonic Neoplasms Comorbidity Female Humans Male Middle Aged Neoplasm Staging Prognosis Risk Factors Elective Surgical Procedures Postoperative Complications Oncology Cancer Research Middle Aged medicine.disease Prognosis Surgery Oncology Elective Surgical Procedures 030220 oncology & carcinogenesis Colonic Neoplasms Female Short-term results Elective Surgical Procedure business |
| Popis: | AIM The aim of this study was to analyze the influence of comorbidities and to compare the short-term results of elective surgical resection of stage I-II colon adenocarcinoma in elderly (≥65 years) versus younger patients. PATIENTS AND METHODS Two groups of sex-matched younger and older patients were compared: Group A: N=36, median age 58 (range=43-65) years; and group B: N=67, median age 73 (range=66-86) years. RESULTS Overall, 71 out of 103 (68.9%) patients had one or more comorbidities. A greater number of older patients had an American Society of Anesthesiologists (ASA) score >2 (p=0.004) and were on multiple medications (polypharmacy) (p=0.016), but the distribution of the other parameters was similar (p≥0.05). Intra- and postoperative complications in group A vs. B occurred in 25.0% vs. 26.9%, and 47.2% vs. 64.2%, respectively (p≥0.05). CONCLUSION Elderly patients with colon cancer scheduled to elective surgical resection should not be considered at increased risk of intra- or short-term postoperative complications with respect to younger patients. However, they require careful individual preoperative evaluation because they are usually polypharmacy users and have a higher ASA score. |
| Databáze: | OpenAIRE |
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