A study of retinal changes in women with polycystic ovarian syndrome

Autor:	KavitaR Bhatnagar, Sakshi Shiromani, Pratibha Singh, Suwarna Suman, Seema Meena, Shadman Parveen
Rok vydání:	2022
Předmět:	Adult Retinal Ganglion Cells Adolescent Cholesterol HDL Cholesterol LDL Middle Aged Ophthalmology Young Adult Nerve Fibers Humans Female Testosterone Tomography Optical Coherence Polycystic Ovary Syndrome
Zdroj:	Indian journal of ophthalmology. 70(10)
ISSN:	1998-3689
Popis:	To compare the optical coherence tomography (OCT)-based retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL) thickness at the posterior pole, and total macular thickness of women with the polycystic ovarian syndrome (PCOS) versus healthy reproductive age group females.The study included 110 eyes of 55 diagnosed cases of PCOS (study group) and 110 eyes of 55 healthy reproductive age group (15-49 years) females (control group). All patients underwent a detailed ophthalmological evaluation followed by an OCT to measure their retinal thicknesses. The body mass index (BMI) of patients was noted and compared with the retinal thickness. Also, the lipid profile and serum testosterone levels of PCOS patients were recorded.The retinal thicknesses in the two study were similar and there was no statistically significant difference. However, on stratification with BMI, it was seen that in patients with BMI30 kg/mAndrogens have a trophic action on nerves, which could explain the increased RNFL thickness in these patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91cd0e0300ac05c685c3604ccfe5db7 https://pubmed.ncbi.nlm.nih.gov/36190052 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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