A case of hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli after pericardiectomy

Autor: Roeun Im, Magnus Halland, Matthew Brian Amdahl, Daniel B. Maselli, June Tome, Daniel Pfeifle, Catherine E. Hagen
Rok vydání: 2021
Předmět:
Zdroj: Clinical Journal of Gastroenterology. 15:123-127
ISSN: 1865-7265
1865-7257
DOI: 10.1007/s12328-021-01539-8
Popis: The majority of cases of Shiga toxin-producing Escherichia coli are self-limited; however, the infection can occasionally be complicated by more severe phenomena, such as thrombotic microangiopathy, with resultant end-organ damage to the kidneys, colon, nervous system, and various other tissues. Shiga toxin-induced hemolytic uremic syndrome (ST-HUS)-the constellation of thrombocytopenia, hemolysis, and renal failure resulting from thrombotic microangiopathy in a subset of infections producing the Shiga toxin-is classically observed in the pediatric population. Nevertheless, the diagnosis should be considered in adults with this presentation, and especially in those with colonic findings suggestive of ischemia. ST-HUS must also be distinguished from other thrombotic microangiopathies and related conditions, such as disseminated intravascular coagulation, thrombotic thrombocytopenic purpura, and complement-mediated HUS, as these diagnoses prompt alternate management strategies. Here, we present a case of ST-HUS in a gentleman following pericardiectomy who was infected with non-O157:H7 E. coli producing Shiga toxin 2.
Databáze: OpenAIRE
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