Haemoglobin and Serum Iron Responses to Periodic Intravenous Iron-Dextran Infusions during Maintenance Haemodialysis
| Autor: | Alexander M Shepherd, L. W. Fleming, W. K. Stewart |
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| Rok vydání: | 1976 |
| Předmět: |
Male
medicine.medical_specialty Iron Intravenous iron Hemoglobins chemistry.chemical_compound Renal Dialysis medicine Humans Blood Transfusion medicine.diagnostic_test business.industry Maintenance haemodialysis Anemia General Medicine Surgery Dextran chemistry Nephrology Anesthesia Injections Intravenous Serum iron Chronic renal failure Female Iron-Dextran Complex business Follow-Up Studies |
| Zdroj: | Nephron. 17:121-129 |
| ISSN: | 1423-0186 0028-2766 |
| DOI: | 10.1159/000180717 |
| Popis: | Patients with chronic renal failure who were on maintenance haemodialysis, were given monthly 600 mg iron intravenously as iron-dextran complex to a body replacement total of 5-6 g iron. Those patients who had been on maintenance haemodialysis for a long period and had received numerous blood transfusions failed to show a rise in haemoglobin levels. Those patients who received iron from the commencement of maintenance dialysis, and who had not received blood transfusions, showed a significant increase in haemoglobin concentrations which has been maintained for more than 18 months after iron therapy ceased, despite a concurrent decrease in serum iron concentrations. Pre-treatment and post-treatment levels of serum iron are not of predictive value for the success of iron treatment, neither for the haemoglobin nor the serum iron response. A body replacement dose of iron given intravenously over a year benefits the majority of patients on maintenance haemodialysis and is recommended for the treatment of their anaemia. |
| Databáze: | OpenAIRE |
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