Prevalence of GBV C/HGV RNA and GBV C/HGV Antibodies in French Volunteer Blood Donors: Results of a Collaborative Study

Autor:	B, Mercier, A, Barclais, C, Botte, J, Cantalube, J, Coste, C, Defer, C, Gautreau, C, Giannoli, P, Halfon, I, Lepot, P, Loiseau, J, Martial, P, Montcharmont, P, Merel, D, Ouzan, N, Ravera, J, Follana, R, Césaire, C, Janot, J, Lemaire, P, De Micco, G, Vezon, C, Férec
Rok vydání:	1999
Předmět:	Adult Male Adolescent Reverse Transcriptase Polymerase Chain Reaction Flaviviridae Blood Donors Hematology General Medicine Middle Aged Reference Values Prevalence Humans RNA Viral Female France Hepatitis Antibodies
Zdroj:	Vox Sanguinis. 76:166-169
ISSN:	1423-0410 0042-9007
DOI:	10.1046/j.1423-0410.1999.7630166.x
Popis:	Posttransfusion hepatitis still occurs at an incidence of about 1 in 118,000 for HBV and 1 in 220,000 for HCV. This collaborative study aimed to determine the prevalence of a novel flavivirus, GBV-C/HGV, even though its role in transfusion-associated hepatitis is uncertain.GBV-C/HGV RNA was detected by PCR using either the Boehringer detection kit or by primers previously described. HGV antibodies were detected by a serological assay from Boehringer.The observed GBV-C/HGV RNA frequency was 3.4%. HGV antibodies occurred in 9.5% of donors.In our study, 12. 9% of the donors had been in contact with the GBV-C/HGV virus.
Databáze:	OpenAIRE
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