Adiposity markers and lung function in smokers: a cross-sectional study in a Mediterranean population

Autor: Ramon Sagarra Àlamo, Josep Basora, Juan José Cabré Vila, Francisco M Martín Luján, Cristina Rey-Reñones, Gemma Flores-Mateo, Rosa SOLÀ, Estefania Aparicio
Přispěvatelé: Alimentació, Nutrició, Creixement i Salut Mental, Unitat de Recerca de Lípids i Arteriosclerosi, Ciències Mèdiques Bàsiques, Medicina i Cirurgia, Universitat Rovira i Virgili
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Male
1471-2466
Vital Capacity
Pulmonary function testing
Body Mass Index
0302 clinical medicine
Forced Expiratory Volume
Fumadors
030212 general & internal medicine
Lung
Abdominal obesity
Adiposity
Ciències de la salut
Waist-to-height ratio
education.field_of_study
medicine.diagnostic_test
Smoking
respiratory system
Middle Aged
Ciencias de la salud
Obesity
Abdominal
Obesitat
Waist circumference
Female
medicine.symptom
Tobacco smoke
Research Article
Spirometry
Pulmonary and Respiratory Medicine
Adult
medicine.medical_specialty
Waist
Population
03 medical and health sciences
FEV1/FVC ratio
Internal medicine
medicine
Humans
Obesity
education
business.industry
Health sciences
Pulmons -- Malalties
Overweight
Lung function test
respiratory tract diseases
Cross-Sectional Studies
030228 respiratory system
Spain
Multivariate Analysis
Physical therapy
Linear Models
business
Body mass index
Biomarkers
Zdroj: BMC Pulmonary Medicine
ISSN: 1471-2466
Popis: Background The aim of this study was to assess the association of key adiposity markers with lung function in smokers without respiratory disease in a Mediterranean population. Methods We performed a cross-sectional study with baseline data from a representative sample of the ESPITAP study in Spain. Participants were 738 smokers (52.3% men) without respiratory disease, aged 35 to 70, selected from 12 primary health care centres. We assessed weight, height, body mass index (BMI), waist circumference (WC) and waist-to-height ratio (WHtR). The pulmonary functional parameters were forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1) and FEV1/FVC ratio. Results In this cohort of smokers, 22.2% of individuals had central obesity. FVC% was inversely associated with all anthropometric measures (BMI, WC and WHtR) in the overall population and in men; in women, only BMI was associated with FVC%. FEV1% was inversely associated to BMI and WC in the overall population, and to all anthropometric measures in men. Furthermore, both BMI and obesity were positively associated with FEV1/FVC ratio overall and when stratified by sex; this suggests a restrictive pattern explained by the altered ventilator mechanics experienced by people with obesity. Conclusion In a Mediterranean population of smokers without respiratory symptoms, abdominal obesity, evaluated not only by BMI and WC but also WHtR, is inversely associated with lung function. Fat distribution appears more strongly related to pulmonary function parameters in men than in women. In smokers with high values for WC, WHtR and BMI, assessment of lung function is recommended. Trial registration Current Controlled Trials NCT01194596 . Registered 2 September 2010.
Databáze: OpenAIRE
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