Requirement of the Adrenal for Certain Urine Electrolyte Effects of Salmon Calcitonin in Rats
| Autor: | Schlueter Rj, Stubbs Rk, Bastian Jw, Aldred Jp, R. R. Kleszynski |
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| Rok vydání: | 1971 |
| Předmět: |
Calcitonin
Male medicine.medical_specialty Epinephrine Hydrocortisone medicine.medical_treatment Natriuresis Electrolyte Urine Sodium Chloride Kidney General Biochemistry Genetics and Molecular Biology Phosphates Furosemide Internal medicine Adrenal Glands medicine Animals Drug Interactions Magnesium Salmon calcitonin Desoxycorticosterone Aldosterone Chemistry Sodium Adrenalectomy Rats Inbred Strains Fasting Diuresis Rats Endocrinology Spectrophotometry Adrenal hormones Creatinine Potassium Calcium Diuretic Salmonidae hormones hormone substitutes and hormone antagonists Triamterene medicine.drug |
| Zdroj: | Experimental Biology and Medicine. 137:1145-1151 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-137-35744 |
| Popis: | SummarySalmon calcitonin, a potent diuretic, natriuretic, phosphaturic agent in the intact rat, was found to be inactive in this regard in the adrenalectomized rat while maintaining full hypocalcemic activity. Pre-treatment of adrenalectomized rats with hydrocortisone alcohol partially restored the natriuretic effect of salmon calcitonin, but did not duplicate effects observed in the intact rat. Other adrenal hormones were independently ineffective in restoring the urine electrolyte effects of salmon CT in the adrenx rat under the experimental conditions utilized. |
| Databáze: | OpenAIRE |
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