Performance in Hand Coordination Tasks and Concurrent Functional MRI Findings in 13-Year-Olds Born Very Preterm
| Autor: | Karoliina Uusitalo, Leena Haataja, Virva Saunavaara, Annika Lind, Victor Vorobyev, Joni Tilli, Riitta Parkkola, Sirkku Setänen, Mikael Ekblad, Satu Ekblad, Eeva Ekholm, Linda Grönroos, Mira Huhtala, Jere Jaakkola, Eveliina Joensuu, Pentti Kero, Riikka Korja, Katri Lahti, Helena Lapinleimu, Liisa Lehtonen, Tuomo Lehtonen, Marika Leppänen, Jaakko Matomäki, Jonna Maunu, Petriina Munck, Laura Määttänen, Pekka Niemi, Anna Nyman, Pertti Palo, Liisi Ripatti, Päivi Rautava, Katriina Saarinen, Tiina Saarinen, Matti Sillanpää, Suvi Stolt, Päivi Tuomikoski-Koiranen, Timo Tuovinen, Anniina Väliaho, Milla Ylijoki |
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| Přispěvatelé: | University of Helsinki, Children's Hospital, HUS Children and Adolescents |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Birth weight CHILDREN Audiology Functional Laterality 3124 Neurology and psychiatry 03 medical and health sciences 0302 clinical medicine TEMPLATE AGE Developmental Neuroscience 3123 Gynaecology and paediatrics Cerebellum 030225 pediatrics Humans Medicine Very Preterm Birth Fine motor Cerebral Cortex MOTOR IMPAIRMENT medicine.diagnostic_test business.industry Functional Neuroimaging Follow-up fMRI 3112 Neurosciences Gestational age Adolescent Development University hospital Magnetic Resonance Imaging Very preterm Neurology Infant Extremely Premature Pediatrics Perinatology and Child Health SKILLS Female Neurology (clinical) business Functional magnetic resonance imaging Prematurity INTEGRATION Psychomotor Performance 030217 neurology & neurosurgery Mri findings Follow-Up Studies |
| Popis: | Background Fine motor and coordination problems are frequently reported among adolescents born preterm. We aimed to assess performance in hand coordination tasks and to compare concurrent brain activation between adolescents born very preterm and at term at 13 years. Methods A total of 34 right-handed adolescents born very preterm (gestational age less than 32 weeks/birth weight ≤1500 grams) and 37 controls born at term during 2003 to 2006 in Turku University Hospital, Finland, were recruited. At 13 years, finger opposition and diadochokinesis were assessed, and brain functional magnetic resonance imaging data were acquired while the adolescents performed unimanual hand coordination tasks in response to visual cue. Results Adolescents born very preterm performed similar to controls in hand coordination tasks. The very preterm group evoked greater brain activation than the controls in the right precentral gyrus and in the right postcentral gyrus during left-hand finger opposition and in the right postcentral gyrus during left-hand diadochokinesis. Within the very preterm group, lower gestational age was associated with reduced activation in the left superior parietal lobule during right-hand diadochokinesis. Regarding left-hand tasks, lower gestational age was associated with stronger activation in the right cerebellar lobule V and left cerebellar lobule VI during finger opposition and stronger activation in the right superior parietal lobule during diadochokinesis. Conclusions Very preterm birth affected hand coordination-related brain activation. Most of the effects were found for nondominant hand. Clinical performance during the hand coordination tasks was similar in adolescents born very preterm and controls. |
| Databáze: | OpenAIRE |
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