Self-Tracking Energy Transfer for Neural Stimulation in Untethered Mice
Autor: | Ada S. Y. Poon, Shrivats Mohan Iyer, Karl Deisseroth, Amelia J. Christensen, Scott L. Delp, John S. Ho, Yuji Tanabe, Logan Grosenick |
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Rok vydání: | 2015 |
Předmět: |
Physics
Physics - Instrumentation and Detectors Property (programming) business.industry Quantitative Biology::Tissues and Organs Energy transfer Wireless transmitter Electrical engineering FOS: Physical sciences General Physics and Astronomy Self tracking Instrumentation and Detectors (physics.ins-det) Dielectric Power (physics) Hardware_GENERAL Quantitative Biology - Neurons and Cognition FOS: Biological sciences Neural stimulation Neurons and Cognition (q-bio.NC) business Physics - Optics Optics (physics.optics) |
Zdroj: | Physical Review Applied. 4 |
ISSN: | 2331-7019 |
Popis: | Optical or electrical stimulation of neural circuits in mice during natural behavior is an important paradigm for studying brain function. Conventional systems for optogenetics and electrical microstimulation require tethers or large head-mounted devices that disrupt animal behavior. We report a method for wireless powering of small-scale implanted devices based on the strong localization of energy that occurs during resonant interaction between a radio-frequency cavity and intrinsic modes in mice. The system features self-tracking over a wide (16 cm diameter) operational area, and is used to demonstrate wireless activation of cortical neurons with miniaturized stimulators (10 mm$^{3}$, 20 mg) fully implanted under the skin. |
Databáze: | OpenAIRE |
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