Mitochondria with tubulovesicular cristae in renal oncocytomas

Autor:	Miguel Angel Martínez, G. Usera Sárraga, H. García Muñoz, C. Bárcena, M. P. Ortega
Rok vydání:	2010
Předmět:	Male Pathology medicine.medical_specialty Incidental Findings Chromophobe Renal Cell Carcinoma Biology Mitochondrion Middle Aged urologic and male genital diseases medicine.disease Kidney Neoplasms Pathology and Forensic Medicine Mitochondria Diagnosis Differential Microscopy Electron Transmission Structural Biology Ultrastructure medicine Biomarkers Tumor Adenoma Oxyphilic Humans Female Renal oncocytoma Carcinoma Renal Cell
Zdroj:	Ultrastructural pathology. 34(6)
ISSN:	1521-0758
Popis:	Renal oncocytoma and chromophobe renal cell carcinoma (CRCC) are closely related tumors. They are considered the extremes of a spectrum with several variants. Ultrastructural examination of the mitochondria is a helpful procedure in the diagnosis of these neoplasms. Renal oncocytomas show mitochondria with piled lamellar cristae, and CRCC exhibited mitochondria with tubulovesicular cristae. In a series of 23 histologically diagnosed renal oncocytomas examined by electron microscopy, the authors found 5 tumors exhibiting more cells with mitochondria showing tubulovesicular cristae. The authors believe these 5 cases present a submicroscopic appearance intermediate between renal oncocytoma and CRCC, although with benign clinical behavior.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e1e5c6aa1fc61c62db558182842fc0 https://pubmed.ncbi.nlm.nih.gov/21070162 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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