Case series and review of Ayurvedic medication induced liver injury
| Autor: | Justin K. Lee, Tse Ling Fong, Christopher M. Karousatos, David R. Braxton |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Drug medicine.medical_specialty Ayurvedic medicine media_common.quotation_subject Alternative medicine Case Report Traditional Chinese medicine Tinospora cordifolia 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Aged media_common Liver injury Roussel Uclaf causality assessment method biology business.industry Herb induced liver injury (HILI) lcsh:Other systems of medicine Middle Aged Jaundice lcsh:RZ201-999 biology.organism_classification medicine.disease Community hospital Medicine Ayurvedic Drug induced liver injury (DILI) Complementary and alternative medicine 030220 oncology & carcinogenesis Female 030211 gastroenterology & hepatology Chemical and Drug Induced Liver Injury medicine.symptom business Ayurveda |
| Zdroj: | BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-11 (2021) BMC Complementary Medicine and Therapies |
| ISSN: | 2662-7671 |
| Popis: | Background Complementary and alternative medicine use among Americans is prevalent. Originating in India, Ayurvedic medicine use in the United States has grown 57% since 2002. CAM accounts for a significant proportion of drug induced liver injury in India and China, but there have been only three reports of drug induced liver injury from Ayurvedic medications in the U.S. We report three cases of suspected Ayurvedic medication associated liver injury seen at a Southern California community hospital and review literature of Ayurvedic medication induced liver injury. Case presentations Three patients presented with acute hepatocellular injury and jaundice after taking Ayurvedic supplements for 90–120 days. First patient took Giloy Kwath consisting solely of Tinospora cordifolia. Second patient took Manjishthadi Kwatham and Aragwadhi Kwatham, which contained 52 and 10 individual plant extracts, respectively. Third patient took Kanchnar Guggulu, containing 10 individual plant extracts. Aminotransferase activities decreased 50% in Conclusions These patients highlight the risk of drug induced liver injury from Ayurvedic medications and the complexity of determining causality. There is a need for a platform like LiverTox.gov to catalog Ayurvedic ingredients causing liver damage. |
| Databáze: | OpenAIRE |
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