New series of aromatic/ five-membered heteroaromatic butanesulfonyl hydrazones as potent biological agents: Synthesis, physicochemical and electronic properties
| Autor: | Serhat Mamaş, Ümmühan Özmen Özdemir, Fatma Hamurcu, Ozan Sanlı Şentürk, Ayla Balaban Gündüzalp |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Organic Chemistry Hydrazone Chronoamperometry Sulfonic acid Carbon-13 NMR 010402 general chemistry Hydrazide 01 natural sciences Medicinal chemistry 0104 chemical sciences Analytical Chemistry Inorganic Chemistry chemistry.chemical_compound chemistry Proton NMR Organic chemistry Reactivity (chemistry) Cyclic voltammetry Spectroscopy |
| Zdroj: | JOURNAL OF MOLECULAR STRUCTURE |
| ISSN: | 0022-2860 |
| DOI: | 10.1016/j.molstruc.2016.03.092 |
| Popis: | The aromatic/five-membered heteroaromatic butanesulfonylhydrazone derivatives; 5-bromosalicylalde hydebutanesulfonylhydrazone(1), 2-hydroxy-1-naphthaldehydebutane sulfonylhydrazone(2), indole-3-carboxaldehydebutanesulfonylhydrazone (3), 2-acetylfuran- carboxyaldehydebutanesulfonylhydrazone(4), 2-acetylthiophenecarboxyaldehydebutane- sulfonylhydrazone(5) and 2-acetyl-5-chlorothiophene carboxyaldehydebutanesulfonyl hydrazone (6) were synthesized by the reaction of butane sulfonic acid hydrazide with aldehydes/ketones and characterized by using elemental analysis, H-1 NMR, C-13 NMR and FT-IR technique. Their geometric parameters and electronic properties consist of global reactivity descriptors were also determined by theoretical methods. The electrochemical behavior of the butanesulfonylhydrazones were investigated by using cyclic voltammetry (CV), controlled potential electrolysis and chronoamperometry (CA) techniques. The number of electrons transferred (n), diffusion coefficient (D) and standard heterogeneous rate constants (k(s)) were determined by electrochemical methods. (C) 2016 Elsevier B.V. All rights reserved. |
| Databáze: | OpenAIRE |
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