Admission clinical and electrocardiographic characteristics predicting an increased risk for early reinfarction after thrombolytic therapy
| Autor: | Liraz Olmer, Izhak Herz, Angela Chetrit, Gabriel I. Barbash, Yochai Birnbaum, Samuel Sclarovsky, Bruria Zlotikamien |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Male
medicine.medical_specialty Myocardial Infarction Infarction Comorbidity Lower risk Diabetes Complications QRS complex Electrocardiography Patient Admission Recurrence Risk Factors Internal medicine medicine Confidence Intervals Diabetes Mellitus Humans Thrombolytic Therapy cardiovascular diseases Myocardial infarction Hospital Mortality Risk factor Aged medicine.diagnostic_test business.industry Smoking Reproducibility of Results Odds ratio Middle Aged medicine.disease Confidence interval Surgery Survival Rate Hypertension Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | American heart journal. 135(5 Pt 1) |
| ISSN: | 0002-8703 |
| Popis: | Background: This study assessed the ability of clinical and electrocardiographic variables routinely obtained on admission to identify patients with acute myocardial infarction treated with thrombolytic therapy at risk of early reinfarction. Methods and Results: The study included 2602 patients who received thrombolytic therapy for acute myocardial infarction. Baseline demographic variables and admission clinical and electrocardiographic variables were compared between patients with and without reinfarction. Multivariable logistic regression technique was used and included recurrent infarction as the dependent variable, and baseline demographic, clinical, and electrocardiographic variables as independent variables. History of hypertension (odds ratio [OR] 1.52, 95% confidence interval [CI] 1.00 to 2.31) and diabetes mellitus (OR 1.59, 95% CI 1.00 to 2.53) were associated with a higher risk, and current smoking was associated with a lower risk (OR [no versus yes] 1.64, 95% CI 1.05 to 2.58) of early hospital reinfarction. Distortion of the terminal portion of the QRS complex (OR 1.86, 95% CI 1.20 to 2.87) and absence of abnormal Q waves on admission (OR 1.54, 95% CI 0.98 to 2.43) were associated with increased risk of early reinfarction. Conclusions: A simple electrocardiographic sign is a reliable predictor of early reinfarction among patients who receive thrombolytic therapy for acute myocardial infarction. (Am Heart J 1998;135:805-12.) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect