Human embryo research in Belgium: an overview
| Autor: | Guido Pennings, Hilde Van De Velde, Sophie Debrock, Usha Punjabi, Seppe Segers, Velichka Kontozova-Deutsch, Heidi Mertes, Andre Van Steirteghem, Björn Heindryckx |
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| Přispěvatelé: | Surgical clinical sciences, Reproduction and Genetics, Reproductive immunology and implantation, Basic (bio-) Medical Sciences, Centre for Reproductive Medicine - Gynaecology, Vriendenkring VUB, UZB Other |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
animal structures Design analysis Oocyte Retrieval Review Biology cryopreservation Cryopreservation 03 medical and health sciences 0302 clinical medicine Belgium Journal Article Humans Supernumerary embryo transfer 030219 obstetrics & reproductive medicine business.industry Outcome measures Obstetrics and Gynecology Embryo Stem Cell Research Therapeutic Human Experimentation Embryonic stem cell Biotechnology 030104 developmental biology Reproductive Medicine embryonic structures Engineering ethics Human medicine business Embryo research |
| Zdroj: | Fertility and sterility |
| ISSN: | 0015-0282 |
| DOI: | 10.1016/j.fertnstert.2017.05.003 |
| Popis: | Objective: To present an overview of the numbers and types of human embryos used in research projects in Belgium from 2007 to 2015. Design: Analysis of all research proposals approved by the Federal Commission for Medical and Scientific Research on Embryos In Vitro. Setting: Not applicable. Patient(s): Not applicable. Main Outcome Measure(s): Number of embryos used for research, number of embryos created for research, and areas of embryo research. Result(s): Since 2007, 15,811 embryos were used for 36 research projects. In total, 10,492 (66%) fresh supernumerary embryos (unfit for transfer or freezing) were used, 4,083 (26%) frozen supernumerary embryos (donated by parents whose child wish was completed or abandoned), and 1,236 (8%) embryos created for research. Most projects focused on research into embryo development. Fresh supernumerary embryos were mainly used for human embryonic stem cell (hESC) research. Frozen supernumerary embryos were almost exclusively used for research into embryo development and for hESC research. Embryos created for research were used for research into embryo development, oocyte research, research into cryopreservation of oocytes, and hESC research. Conclusion(s): Having concrete data on embryo research is crucial for an informed debate. Moreover, these data are necessary to find out trends in research such as the numbers of embryos needed and the areas of research. Data collection requires a sufficiently clear definition of "research'' and "embryo.'' These conceptual questions frequently reveal lack of clarity in legislation. (C)2017 by American Society for Reproductive Medicine. |
| Databáze: | OpenAIRE |
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