Spinal cord compression as a result of Rosai–Dorfman disease of the upper cervical spine in a child

Autor: W. Jerry Oakes, Elizabeth Mroczek-Musulman, Roger L. Berkow, Paul A. Grabb, David R. Kelly, Yuki Hammers, R. Shane Tubbs
Rok vydání: 2005
Předmět:
Zdroj: Child's Nervous System. 21:951-954
ISSN: 1433-0350
0256-7040
DOI: 10.1007/s00381-004-1121-1
Popis: Rosai–Dorfman disease is characterized by massive painless cervical lymphadenopathy, but can also include nasal obstruction, tonsillar enlargement, or hearing abnormalities. The disease occurs most often in the third and fourth decades. Most authors have suggested that it represents either an autoimmune disease or a reaction to an infectious agent that has yet to be discovered. Less than 50 cases of central nervous system involvement have been reported. We report a child with cervical spinal cord compression due to Rosai–Dorfman disease of the cervical spine. This disease has variable outcomes from relatively benign to insidious over decades. Our case is unusual in that the patient was a child and had involvement of the spine with resultant cord compression, a combination that has been reported rarely.
Databáze: OpenAIRE