Introns in Cryptococcus
| Autor: | Guilhem Janbon |
|---|---|
| Přispěvatelé: | Biologie des ARN des Pathogènes fongiques - RNA Biology of Fungal Pathogens, Institut Pasteur [Paris], Acknowledgements to Cecelia Shertz Wall for editing the manuscript., Institut Pasteur [Paris] (IP) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Transposable element MESH: Sequence Analysis DNA lcsh:Arctic medicine. Tropical medicine intron lcsh:RC955-962 030106 microbiology lcsh:QR1-502 Cryptococcus Review yeast lcsh:Microbiology 03 medical and health sciences alternative splicing DNA Fungal Gene [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology Cryptococcus neoformans Genetics [SDV.GEN]Life Sciences [q-bio]/Genetics biology Alternative splicing Intron RNA MESH: Cryptococcus / genetics Sequence Analysis DNA Genome project biology.organism_classification Introns MESH: DNA Fungal 030104 developmental biology MESH: Introns / genetics MESH: Genome Fungal Genome Fungal |
| Zdroj: | Memórias do Instituto Oswaldo Cruz Memórias do Instituto Oswaldo Cruz, Instituto Oswaldo Cruz, Ministério da Saúde, 2018, 113 (7), pp.e170519. ⟨10.1590/0074-02760170519⟩ Memórias do Instituto Oswaldo Cruz, 2018, 113 (7), pp.e170519. ⟨10.1590/0074-02760170519⟩ Memórias do Instituto Oswaldo Cruz, Volume: 113, Issue: 4, Article number: e170519, Published: 19 FEB 2018 Memórias do Instituto Oswaldo Cruz, Volume: 113, Issue: 7, Article number: e170519, Published: 19 FEB 2018 Memórias do Instituto Oswaldo Cruz., Vol 113, Iss 7 (2018) |
| ISSN: | 0074-0276 1678-8060 |
| DOI: | 10.1590/0074-02760170519⟩ |
| Popis: | International audience; In Cryptococcus neoformans, nearly all genes are interrupted by small introns. In recent years, genome annotation and genetic analysis have illuminated the major roles these introns play in the biology of this pathogenic yeast. Introns are necessary for gene expression and alternative splicing can regulate gene expression in response to environmental cues. In addition, recent studies have revealed that C. neoformans introns help to prevent transposon dissemination and protect genome integrity. These characteristics of cryptococcal introns are probably not unique to Cryptococcus, and this yeast likely can be considered as a model for intron-related studies in fungi. |
| Databáze: | OpenAIRE |
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