Carpentier–Edwards supraannular porcine bioprosthesis: second-generation prosthesis in aortic valve replacement
| Autor: | Eva Germann, Lawrence H. Burr, Robert T. Miyagishima, Hilton Ling, Michael T. Janusz, W.R. Eric Jamieson |
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| Rok vydání: | 2001 |
| Předmět: |
Male
Reoperation Pulmonary and Respiratory Medicine Aortic valve medicine.medical_specialty medicine.medical_treatment Prosthesis Design Prosthesis Postoperative Complications Aortic valve replacement Actuarial Analysis Internal medicine Case fatality rate Humans Medicine Survival analysis Aged Aged 80 and over Bioprosthesis business.industry Clinical performance Middle Aged medicine.disease Survival Analysis Surgery medicine.anatomical_structure Aortic Valve Heart Valve Prosthesis Concomitant Cardiology Female Cardiology and Cardiovascular Medicine business Artery |
| Zdroj: | The Annals of Thoracic Surgery. 71:S224-S227 |
| ISSN: | 0003-4975 |
| DOI: | 10.1016/s0003-4975(01)02549-8 |
| Popis: | Background . The Carpentier–Edwards supraannular porcine bioprosthesis experience for more than 18 years has been evaluated by actuarial and actual analysis to determine the clinical performance in aortic valve replacement. Methods . From 1981 to 1998, 1,823 patients (mean age 68.5 years, range 20 to 90 years) underwent 1,846 procedures. Previous coronary artery bypass was performed in 3.1% (56) and previous valve repair/replacement in 6.0% (110). Concomitant coronary artery bypass grafting was performed in 41.5% (756). Results . The overall valve-related complication rate was 4.5%/patient-year (567 patients) with a fatality rate of 0.9%/patient-year (110 patients). The patient survival, at 15 years, was 33.0% ± 3.7% for the 61 to 70 years age group and 13.5% ± 2.4% for the older than 70 years group. At 15 years, the overall actual, cumulative freedom from reoperation was 83.2% ± 1.4%, valve-related mortality was 88.0% ± 1.2%, and valve-related residual morbidity was 92.0% ± 0.8%. The actual freedom from structural valve deterioration at 15 years was 84.2% ± 2.8% for the 61 to 70 years group and 97.1% ± 0.9% for the older than 70 years group. Conclusions . The Carpentier–Edwards porcine bioprosthesis provides excellent freedom from structural valve deterioration, and overall freedom from valve-related morbidity, mortality, and reoperation for aortic valve replacement for up to 15 years. The prosthesis is recommended for patients older than 70 years and for patients 61 to 70 years, especially when extended survival is not anticipated. |
| Databáze: | OpenAIRE |
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