Use of Wittig reaction for the synthesis of conjugated Aza-BODIPYs and their spectral and electrochemical properties
| Autor: | Mangalampalli Ravikanth, Angira Koch, Sunit Kumar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Suzuki Coupling
Conjugated system 010402 general chemistry Electrochemistry 01 natural sciences Biochemistry chemistry.chemical_compound Wittig Reaction Drug Discovery Organic chemistry Dyes Sensor Reaction conditions 010405 organic chemistry Chemistry Organic Chemistry Fluorescence 0104 chemical sciences Photophysical Studies Wittig reaction Photodynamic Therapy Aza-Bodipy Absorption (chemistry) Two-dimensional nuclear magnetic resonance spectroscopy Boronic acid |
| Zdroj: | IndraStra Global. |
| ISSN: | 2381-3652 |
| DOI: | 10.1016/j.tet.2017.01.058 |
| Popis: | The 2-formyl 1,3,5,7-tetraaryl aza-BODIPY and 2-formyl-6-bromo 1,3,5,7-tetraaryl aza-BODIPY were subjected to Wittig reaction with three different ylides under simple reaction conditions and afforded the conjugated aza-BODIPYs in high yields. The aza-BODIPYconjugates resulted from 2-formyl-6-bromo aza-BODIPYs were reacted further with 4-anisyl boronic acid under mild Pd(0) coupling conditions and afforded 1,2,3,5,7-pentaaryl aza-BODIPYconjugates. The method works efficiently and allows to introduce different substituents at the aza-BODIPY core. All compounds were characterized by HRMS, 1D, 2D NMR, absorption, fluorescence and electrochemical techniques. The spectral and electrochemical studies indicated that the introduction of conjugated substituents at the aza-BODIPY core alter the electronic properties significantly. (C) 2017 Elsevier Ltd. All rights reserved. |
| Databáze: | OpenAIRE |
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