Coronary Vascular Development in Response to Increased Right Ventricular Pressure Loads
| Autor: | John H.K. Vogel, Robert F. Grover, H. R. Overy, S. G. Blount |
|---|---|
| Rok vydání: | 1966 |
| Předmět: |
Cardiac Catheterization
medicine.medical_specialty Physiology Heart Ventricles Lumen (anatomy) Blood Pressure In Vitro Techniques Pulmonary Artery Right ventricles Muscle mass Age groups medicine.artery Internal medicine Pressure Ventricular muscle medicine Animals Sheep business.industry Angiography Hypertrophy Organ Size Coronary Vessels Ventricular weight Animals Newborn Right coronary artery Hypertension Cardiology Ventricular pressure Cardiology and Cardiovascular Medicine business |
| Zdroj: | Circulation Research. 18:634-640 |
| ISSN: | 1524-4571 0009-7330 |
| Popis: | Pressure loads were applied to the right ventricles of newborn lambs and adult sheep by surgical narrowing of the lumen of the main pulmonary artery. Significant increases in right ventricular weight and in the diameter of the right coronary artery occurred in both age groups of animals, compared with corresponding control animals. The evidence suggests that the degree of increase in the arterial diameters, relative to the increase in ventricular muscle mass, is similar in both newborn and adult animals. However, the results suggest also that the capacity to respond to pressure loads, in terms of increased muscle mass, is relatively greater in the newborn animals than in the adults. |
| Databáze: | OpenAIRE |
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